摘要
为观察强脾补精化瘀益智胶囊对多发梗塞性痴呆 ( MID)的临床疗效 ,选择符合中西医诊断标准及中医辨证属脾肾两虚兼气滞血瘀 1 1 0例 ,随机分为强脾补精化瘀益智胶囊治疗组与脑复康对照组 ,疗程 3个月 ,同时检测患者 6-酮 -前列腺素 F1α( 6-KP)、血栓素 B2 ( TXB2 )的变化。结果治疗组总有效率为 76.79% ,对照组总有效率 5 0 % ,治疗组血浆 6-KP明显高于对照组、TXB2 值明显低于对照组 ,2组比较差异有非常显著性意义。说明强脾补精化瘀益智胶囊能升高 MID患者血浆 6-KP,降低 TXB2 ,恢复 PGI2 和 TXA2 之间的动态平衡 ,扩张脑血管 ,改善脑循环 ,抗血小板聚集 ,防止血栓再形成 ,从而起到治疗多发梗塞性痴呆的作用。
To observe the therapeutic effect of Qiangpibujinghuayuyizhi capsule to multi-infarct dementia,selecting 110 cases asthenia of both the spleen and kidney and qi-stagnancy and blood stasis type according to TCM and western medicine diagnostic standards.Dividing them randomly into therapeutic group and Piracetam contrast group with 3 months course of treatment and determine the changes of 6-kp and TXB 2.The results showed that total effective power was 76.79% in therapeutic group and 50% in contrast group,6-kp value was obviously higher in therapeutic group while TXB 2 value was obviously higher in contrast group.There was very significant difference between these two groups.It is proved that Qiangpibujinghuayuyizhi capsule can enhance plasma 6-kp,lower TXB 2 and get back the dynamic balance between PGI 2 and TXA 2.It can treat multi-infarct demenia through broadening cerebral vessles,improving cerebral circulation,inhibiting platelet aggregation and preventing thromosis.
出处
《福建中医学院学报》
2004年第5期1-3,共3页
Journal of Fujian College of Traditional Chinese Medicine
基金
福建省青年科技创新基金资助项目 ( 2 0 0 1J0 60 )
