对溴苯甲醛合成新工艺

A New Synthetic Method of p-Bromobenzaldehyde

用三氧化二锰直接氧化法将对溴甲苯氧化对溴苯甲醛,讨论了合成过程中影响产率的各种因素,确定反应的优化条件为温度338K,硫酸的浓度7.5mol/L,三氧化二锰1.8g,产率可达73.89%。并对不同硫酸浓度下Mn3+氧化对溴甲苯的反应动力学进行了研究。该方法具有工艺简单,条件温和,对环境不造成污染,易于工业化生产等优点。

p-Bromobenzaldehyde was synthesized from p-bromotoluene by direct oxidation with manganese sesquioxide The factors affecting the yields of p-bromobenzaldehyde were investigated. The optimum conditions of this new synthetic reaction are: manganese susquioxide, 1.8 g; sulfuric acid, 7.5 mol/L; and reaction temperature, 338 K. The yield of p-bromobenzaldehyde is 73.89%. The kinetics of the oxidation reaction using Mn^3+ as oxidant was also studied. In this new synthetic route, the yield is high, the quality of product is good, and the operations are simple. The process has a bright prospect for industrialization.