洋紫荆中化学成分的分离与鉴定

Isolation,identification of the chemical constituents from Bauhinia variegata L.

目的研究洋紫荆中的化学成分。方法采用硅胶、聚酰胺、SephedexLH 2 0柱色谱分离纯化 ,理化常数和谱学方法鉴定结构。结果分离得到 7个化合物和 1个混合物 ,鉴定为friedelin(1)、2 4 (R) 9,19 cyclolanost 3 one 2 4 ,2 5 diol(2 )和 2 4 (S) 9,19 cyclolanost 3 one 2 4 ,2 5 diol(3)的混合物、豆甾烷 3 酮 (4 )、豆甾烷 4 烯 3 酮 (5 )、豆甾烷 3β 醇 6 酮 (6 )、豆甾烷 5 烯 3β 醇 7 酮 (7)、β 谷甾醇 (8)、大黄素甲醚 (9)。结论化合物 2和 3的混合物、5、7、9为首次从该属植物中分离得到。

Aim To study the chemical constitu en ts of Bauhinia variegata L.Methods The compounds were isolat ed by the chroma tography methods and identified by spectroscopic analysis.Result Seven compounds and a mixture were obtained and identified as friedelin(1),24(R)-9,19-cyclolanost-3-one-24,25-diol(2)and 24(S)-9,19-cyclolanost-3-one-24,25-diol(3),stigmast-3-one(4),stigmast-4-en-3-one(5),stigmast-3β-ol-6-one(6),stigmast-5-en -3β-ol-7-one(7),β-sitosterel(8),physicion(9).Conclusion Compounds 2,3,5,7,9 are obtained from this plant for the first time.