急性缺血性脑卒中的TOAST亚型分析

TOAST subtyping of acute ischemic stroke

目的 依据TOAST方法对缺血性卒中人群进行亚型分析 ,总结缺血性卒中发病的病因学特征。方法 2 0 0 2年 7月至 2 0 0 3年 2月因首发缺血性卒中在我科住院治疗患者 30 0例 ,经磁共振成像、磁共振血管造影、数字血管造影等影像学检查及其他病因学检查 ,依据TOAST分型标准确定每个患者所属亚型。结果 本组患者TOAST亚型的构成比例为 :心源性脑栓塞 12 3% ,大动脉粥样硬化性卒中 4 0 0 % ,小动脉卒中 31 3% ,其他原因引发的缺血性卒中 5 0 % ,原因不明的缺血性卒中 11 4 %。结论 本组患者在不同性别之间 ,TOAST亚型构成比的差异没有统计学意义。本组患者的大动脉粥样硬化性卒中所占比例高于其他 4个亚型。

ObjectiveTo determine the etiologicalcharacterictics of ischemic stroke in Chinese people on the basis of Trial of Org 10 172 in Acute Stroke Treatment (TOAST) criteria.Methods300 patients with ischemic stroke were recruited into this study. Ischemic stroke was classified into five subtypes based on clinical manifestations,MRI,MRA and DSA.ResultsOf all the ischemic stroke patients,12.3%,40.0%,31.3%,5.0%,and 11.4% were classified as cardioembolicm,large-artery atherosclerotic,lacunare,of other demonstrated etiology and of undetermined etiology.ConclusionsThe statistical comparison between male and female of each subtype is not significant. The relative incidence of large-artery atherosclerosis in Chinese patients is higher than that of all the other four subtypes.