2223例正常孕妇血清甲胎蛋白含量的测定

Study of AFP level in the blood serum of the 2223 normal pregnant women

以整群抽样采用放射免疫分析法(RIA)对2223例不同孕期、不同年龄的正常孕妇血清甲胎蛋白(AFP)的含量进行测定并进行统计分析。结果表明,孕期在12周以内者,其血清AFP在正常范围以内,自13周开始逐渐缓慢上升,至32周达最高水平(184.6±74.6μg/l),以后呈缓慢下降趋势,至临产期仍维持在100μg/l以上。提示正常孕妇不同孕期血清AFP有明显的规律性。孕妇血清AFP水平的高低与孕妇的年龄无明显关系(p>0.05)。

In this paper, the authors have reported AFP level in the blood serum of 2223 normal pregnant women in different semesters by RIA method. All the data were made by statistical analysis. The result has shown that the AFP level was normal during the first 12 weeks of pregnancy. Then, it gradually increases from the 13th week and reaches its maximum(184.6±74.6 μ g/l) at 32nd week. Later on it tends to decrease slowly, but still remains over 100 μg/l in parturient period. Therefore, it was suggested that AFP in pregnant women have substantial difference and regularity between different semesters but without any significant correlation with their ages.