高效液相色谱法测定从酚焦油裂解液中回收的苯乙酮含量

Determination of acetophenone recovered from phenol tar by HPLC

报道了高效液相色谱法测定苯酚焦油裂解液中苯乙酮的含量。采用SpherisorbC18色谱柱(2 5 0mm× 4 .6mm ,5 μm) ,乙腈 /水 /醋酸 (体积比 6 0 :39:1)为流动相 ,流速 1.0mL·min-1,检测波长 2 4 5nm。结果表明 :苯乙酮在 0 .5～ 10 2× 10 -3 g·L-1浓度范围内线性关系良好 (r =0 .9998) ,RSD不大于 1.1%。该法操作简单、快速、准确 ,适合于苯酚焦油中回收苯乙酮的生产过程分析和成品质量检验。

The HPLC system, consisted of Spherisorb C 18 column (250mm×4.6mm,5μm), acetonitrile-water-acetic acid(60:39:1) mixture as mobile phase ( flow rate 1.0mL·min -1 at room temperature) and with UV detection at 245nm,was used to determine the content of acetophenone. The linear range was sample injection 0.5～102×10 -3g·L -1( r =0.999 8).The recovery was 98.9～101%,RSD≤1.1%.This method is simple sensitive and accurate.It could be used as the process and quality control means in acetophenone from phenol tar.