老年胰腺癌临床诊治分析

Analysis of clinical diagnosis and therapy in elderly patients with pancreatic cancer

目的 :评估随访老年胰腺癌临床特点和诊治。方法 :总结分析 33例老年胰腺癌临床表现 ,诊断和治疗 ,随访至终点事件发生。结果 :首发症状为腹痛者 2 0例占总数的 6 0 % ,无症状查体发现仅 3例。肿瘤位于胰头部者 17例 (5 2 % )。死亡 30例 ,健存 3例。生存时间为 1～ 2 2个月 ,中位生存时间平均 4 .5月。生存期超过 12个月者有 3例。手术切除肿瘤者仅 2例 ,6例应用健择化疗者 ,2例肿瘤有缩小达到部分缓解。结论 :应重视提高老年胰腺癌诊治水平。进展期胰腺癌健择化疗有一定作用。

Objective:To evaluate and investigate clinical chracterization and therapy in elderly patients with pancreatic cancer. Methods:Clinical manifestation, diagnosis and therapy in 33 elderly patients with pancreatic cancer were analized. End point was followed up. Results:Abdominal pain as first symptom of pancreatic cancer occurred in 20 cases (60%), non-symptom patients with pancreatic cancer occurred only in 3 cases. There were 17 cases in which tumors located in pancreatic head (52%). Among 33 patients, 30 cases were dead and 3 cases still alive. Survival time in these patients was from 1 month to 22 months. Mean survival time was 4.5 months. 3 patients were survival for over 12 months. There were 2 cases in which the tumor resection was performed surgically. Chemotherapy using gemcitabine was performed in 6 patients. There were 2 patients who had partial regression. Conclutions:It is important to pay attention to the diagnosis and therapy in elderly pancreatic cancer patients. Gemcitabine therapy can be used in advanced pancreatic cancer.