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慢性丙型肝炎抗病毒治疗的进展 被引量：1

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摘要 1 丙型肝炎的流行情况 丙型肝炎病毒(HCV)感染流行广泛,呈全球性分布,全球HCV感染者约为1.7亿人.我国在1992年全国病毒性肝炎血清流行病学调查,HCV感染率为3.2%,约为3700万人.
作者 斯崇文
机构地区 北京大学第一医院
出处 《临床肝胆病杂志》 CAS 北大核心 2004年第4期213-215,共3页 Journal of Clinical Hepatology
关键词 慢性丙型肝炎 抗病毒治疗 影响因素 干扰素A 病毒唑
分类号 R512.63 [医药卫生—内科学]
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参考文献10

  • 1Marnus MP, McHutchison JG, Godon SC, et al. Peginteron alfa- 2b plus ribavirin conpared with interferon alfa- 2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial[J]. Lancet, 2001,358:958- 65.
  • 2Hadziyannis SJ, Cheinquer H, Morgan T, et al. Peg- interferon alfa2a(40KD) (Pegasys)in combination with ribaviin: Efficacy and safety results from a phase Ⅲ, randomized, double- blind, multicentre study examing the efect of duration of treatmet and ribav
  • 3Davis GL, Wong JB, McHutchison JG, et al. Early virologic response to treatment with peginterferon alfa - 2b plus ribavirin in patients with chronic hepatitis C[JJ]. Hepatology, 2003, 38:645- 52.
  • 4McHutchison JG, Gorden SC, Schiff ER, et al. Interferon alfa- 2b alone or in conbination with ribavirin, initial treatment for chronic hepatitis C[J].N Engl J Med, 1998,339:1485-92.
  • 5De Francesco R, Rice CM. New therapies on the horizon for hepatitisC:are we close? [J].Clin Liver Dis, 2003,7:211-42.
  • 6Poynard T, Marcellin P, Lee SS, et al. Randomised trial of interferon alfa 2b plus ribavirin for48 weeks or for 24 weeks for treatment of chronic infection with hepatitis C virus[J] .Lancet, 1998,352:1426- 32.
  • 7Fried MW, Shiffman ML, Reddy KR, et al. Conbination of peginterferon alfa- 2a plus ribavirin in patients with chronic hepatitis C virus infection[JJ]. N Engl JJ Med, 2002,347:975-82.
  • 8Ferrenci P,Shiffman ML, Fried MW, et al. Early prediction of respon1se to 40KDA peginterferon alfa 2a(PEGASYS) plus ribavirin in patients with chronic hepatitis C[J] .Hepatology, 2001,34:351A.
  • 9Alberti A, Benvegnu L.Management of hepatitis C [J]. J Hepatology,2003, 38:S104- S118.
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同被引文献9

  • 1刘平.Beck抑郁问卷(Beck Depression Inventory,BDI)[J] .中国心理卫生杂志,1999,(增刊):191-194.
  • 2Bonaccorso S, Marino V, Biondi M, et al. Depression induced by treat- ment with interferon -alpha in patients affected by hepatitis C virus[J]. J Affect Disord, 2002,72(3) :237 -241.
  • 3Franzen PL, Buysse DJ, Rabinovitz M, et al. Poor sleep quality pre- dicts onset of either major depression or subsyndromal depression with ir- ritability during interferon -alpha treatment[ J]. Psychiatry Res, 2010, 177(1 -2) :240 -245.
  • 4Lotrich FE, Rabinovitz M, Gironda P, et al. Depression following pegy- lated interferon - alpha: Characteristics and vulnerability [ J ]. J Psyeho- sore Res, 2007,63(2) :131 -135.
  • 5Horikawa N, Yamazaki T, Izumi N, et al. Incidenee and clinical course of major depression in patients with chronic hepatitis type C undergoing interferon- alpha therapy: a prospective study [ J ]. Gen Hos Psychia- try, 2003,25(1) :34 -38.
  • 6Asnis GM, Garza RDL. Interferon - induced depression in chronic hep- atitis C : a review of its prevalence, risk factors, biology, and treatment approaches[ J]. J Clin Gastreenterol, 2006,40(4) :322 - 335.
  • 7Raison CL, Borisov AS, Broadwell SD, et al. Depression during pegy- lated interferon - alpha plus ribavirin therapy : prevalence and prediction [J]. J Clin Psychiatry, 2005,66(1) :41 -48.
  • 8Rymaszewska J, Kiejna A, Hadrys T. Depression and anxiety in coro- nary artery bypass grafting patients[J]. Eur Psychiatry, 2003,18(4) : 155 - 160.
  • 9Erim Y, Tagay S, Beekmann M, et al. Depression and protective fac- tors of mental health in people with hepatitis C : A questionnaire survey [J]. Int J Nurs Stud, 2010,47(3) :342 -349.

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临床肝胆病杂志
2004年 第4期

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