有机锡用于催化δ-酮腈异构化成吡啶酮的研究

The Isomerization of δ-keto Nitriles to Pyridones Catalyzed by Organotin

本文首次使用有机锡催化δ-酮腈异构化反应成吡啶酮,对三种有机锡(BuSnO_(3/2),Cat.1 ;Bu_2Sno,cat.2;Bu_3SnF,cat.3)催化剂的活性进行了比较,并考察了反应温度、反应时间和催化剂用量等对产率的影响。

The organotin compounds as a kind of catalyst were used to the iso- merization Of δ-keto nitriles for the first time.The catalytic activity of three organotin compounds[BuSnO_3/2(Cat.1);Bu_2SnO(Cat.2);Bu_3SnF(Cat.3)]was compared. The effect of amount of Cat.1,reaction time and temperature on the reaction yield were investigated.