原发性胸椎原始神经外胚层肿瘤的动态增强MRI表现

Dynamic contrast enhanced MRI study of primary primitive neuroectodermal tumor in the thoracic spine

目的 初步探讨原始神经外胚层肿瘤(PNET)的动态增强MRI表现,以及对其诊断及鉴别诊断的价值。方法 用动态增强MRI方法对已手术和病理证实的2例胸椎PNET行3次MR检查并进行前瞻性研究。结果 在信号强度-时间和对比增强率-时间曲线上,2例PNET 3次检查均表现为快升慢降型,即肿瘤早期就开始迅速增强,上升峰极陡,60-120 s即达到高峰水平,然后保持平坦,3.5 min内未见明显下降曲线。结论 动态增强MRI扫描能帮助对PNET进行早期诊断和鉴别诊断,从而为临床选择治疗方案及估计预后提供较为可靠的依据。

Objective To investigate the value of dynamic contrast-enhanced MR imaging in the diagnosis and differentiation of primitive neuroectodermal tumor (PNET) in the thoracic spine. Methods The dynamic contrast-enhanced MR imaging of 2 patients (3 times) with PNET in the thoracic spine proved by surgery and pathology were prospectively studied. Results In the curves of Si-time and CER-time, PNET in the thoracic spine showed a rapid rise to the peak between 60 s and 120 s,then the flat level was kept and no obvious decline was detected after about 3. 5 minute. Conclusion Dynamic contrast-enhanced MRI can help to make the diagnosis and differential diagnosis for PNET in the thoracic spine, offer reliable information for the choice of clinical management, and predict the prognosis.