摘要
血小板源性生长因子(PDGF)在机体伤口愈合过程中具有重要的调节作用。由于角膜的特殊结构和功能,其伤口愈合的调节显得至关重要。本文简述PDGF的结构、受体、生物学活性及其在角膜伤口愈合中的作用。
Platelet-derived growth factor (PDGF) is soluble singaling proteins affecting the process of normal wound healing. Cornea is a transparent and elastic tissue without blood vessels and about 0.5mm thick in the central part. It consists of three cell layers, namely epithelial cells, interstitial cells and endothelial cells. Thus it is important to understand the mechanism of corneal wound healing in the maintenance of good visual function. In the present article, we reviewed the roles of PDGF in corneal wound healing and the structure, receptors and bio logical characteristics of PDGF.·
出处
《国际眼科杂志》
CAS
2004年第4期664-667,共4页
International Eye Science
基金
中国国家自然科学基金资助项目(No.30070801)
