摘要
目的 比较边境地区 ,元江流域疟疾流行水平 ,以评价其防治效果。 方法 以滤纸干血滴按IFAT常规操作方法进行试验 ,用可逆催化模型R =Y/1-e-rt·r的公式推算年感染概率。 结果 1993~ 1999年边境地区、元江流域全人群抗体阳性率分别下降 2 1 60 %和 5 1.0 0 % ,低龄组居民的抗体阳性率分别下降 15 5 4%和 19 5 2 % ,疟疾年感染概率分别下降 16 98%和 2 0 % ,抗体水平随年龄的增长而升高 ,边境地区的抗体阳性率高于元江流域。中缅边境 ,中越边境境内全人群抗体阳性率 1999年比 1993年分别下降 0 97%和 3 1 76% ,低龄组居民的抗体阳性率分别下降3 7 95 %和上升 5 88% ,疟疾年感染概率下降 3 7 2 9%和 3 9 2 9% ;境外居民的抗体阳性率明显高于境内 ,中缅边境的抗体水平高于中越边境。 结论 两边境的抗体水平随年龄的增长而升高 ,境外高于境内 ;低龄组居民的抗体水平的升降与相应发病率的升降相一致 ,且低龄组的疟疾易感性较大。
Objective To compare malaria prevalence degree and control effect in bordering area and Yuanjiang river valley areas. Methods Blood samples collected on filter paper was tested by IFAT. R=Y/1-e -rt ·r formula was used to calculate the annually infective rate. Results The positive rates dropped by 21.60% and 51.00% in 1999 than 1993 in bordering area and Yuanjiang river valley areas, and those of low age groups(1~15years) dropped by 15.54% and 19.52%. The antibody level increased significantly with the increase of age, and that was higher in bordering area than in Yuanjiang valley. The positive rates dropped by 0.97% and 31.76% in 1999 than 1993, at China-Myanmar and-Laos border areas; and those of low age groups(1~15years) dropped by 37.95% at China-Myanmar border, but increased 5.88% in China-Laos border areas; The overall malaria infection rates dropped by 37.29% and 39.29% in 1999 than in 1993. The antibody level of foreigners was higher than that of Chinese residents, and those at China-Myanmar bordering area was higher than those at China-Vietnam bordering area. Conclusion The positive rate of IFAT and positive GMRT was increased with age in these areas, and external positive rates of IFAT and positive GMRT was higher than internal ones. The low age groups are highly vulnerable to malaria infection.
出处
《中国热带医学》
CAS
2004年第5期749-750,共2页
China Tropical Medicine