探讨应用QCT诊断骨质疏松症

Investigation of using QCT to diagnosis osteoporosis

目的 应用QCT检测成年人L3 BMD探讨诊断骨质疏松症标准。方法 复查 1998年以来普查检测成年人L3 BMD的原始资料 76 3份 ,从中找出能随访受检者健康状况的资料 5 10份 ,男 2 13人 ,女 2 97人 ,年龄 2 0～ 86岁 ,10岁为 1个年龄组进行统计分析 ,同时对其中低BMD者进行健康状况及生活方式的问卷调查。结果 (1)峰值BMD位于 30岁年龄组 ,男性 (2 38 0± 30 1)mg/cm3 ;女性(2 4 2 4± 31 2 )mg/cm3 。 (2 )修正[1] 诊断OP标准为骨密度低于均值 - 2 0标准差 (公式 :BMD <x - 2 0SD)。 (3)修正[1] 诊断OP的分级诊断标准为 3级及诊断量化表。结论 ①修正后的诊断标准 ,符合临床实际病例 ,减少漏诊率 ;②应用分级诊断标准可为科学研究OP及临床观察药物疗效 ,提供具体客观指标及科学依据 ;③诊断量化表可供临床医师查表 ,直接准确、快捷地做出OP的分级诊断 ,并易于推广应用。

Objective To approach osteoporosis diagnoses criteria via determining adults lumber vertebra L 3-BMD with QCT. Methods 763 adults lumber vertebra L 3-BMD information determined from 1998 to now was gathered. 510 subjects in them was able to be visited(male 213, female 297). We visited them and made inquiry about their health status, as well as their life habit. We made statistics analysis with the data we had gotten by age group (10 years is a group). Results (1) The L 3-BMD peak value located at the 30 years old age group, male (238.0±30.1)mg/cm3; female(242.4±31.2)mg/cm2. (2) It is better that OP diagnoses criteria was corrected as this formula: (L 3-BMD<x-2.0 SD). (3) The classification diagnoses criteria (three grades) was corrected, in addition, the quantified diagnoses table was corrected. Conclusion (1)The corrected diagnoses criteria was more appropriate for clinical case. It shall decrease diagnosis rate. (2) The adopting of classification diagnoses criteria will provide scientific, objective, concrete index and grounds for researching OP and estimate OP medicine curative effect in clinic. (3) The quantified diagnoses table will help physician to make classification diagnoses of OP more immediately, more well and truly.