肝移植后巨细胞病毒感染

Cytomegalovirus Infection after Liver Transplantation

目的 探讨临床肝移植后巨细胞病毒 (CMV)感染的一般特征、临床表现以及诊断和防治方法。方法 检索近 10年来国内、外有关文献并综述。结果 临床肝移植后发生CMV感染率较高 ,常并发其它类型的感染性疾病 ,其临床表现无特异性 ,对CMV感染的早期诊断和防治尚缺乏有效措施。结论 CMV是临床肝移植后最重要的机会致病病毒 ,重视术前、术后CMV感染的监测 ,积极预防和早期治疗是关键。

Objective To study the characteristics, diagnosis, treatment and prophylaxis of cytomegalovirus (CMV) infection after liver transplantation. Methods The literatures of recent 10 years were collected and reviewed. Results The infection rate of CMV after liver transplantation was high, and it was frequently complicated with other types of infectious diseases. There was no specificity in the clinical features of CMV infection, and no effective measures were taken for early diagnosis, prevention and therapy. Conclusion CMV is the primary opportunistic pathogen after liver transplantation. Monitoring the status of CMV infection in recipients preoperatively and postoperatively, early prophylaxis and treatment are very important and useful to prevent and treat this disease.