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神经干细胞分化及诱导的研究进展 被引量：1

The differentiation and induction of neural stem cells
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摘要 神经干细胞 (NSC)的分化及诱导是目前神经科学研究的热点。因其有着巨大的潜在应用价值和重大的理论研究意义 ,越来越引起学者们的关注。为此 ,作者从NSC的体内发育、分化开始 ,到体外培养分化诱导的研究 ,从内因 (基因 )和外因 (细胞因子、微环境 )两个方面对近年来NSC诱导分化研究的一些进展作一综述。 The differentiation and induction of neural stem cells (NSC), the most highlights in neuroscience at present is valuable application potency and great significance in theoretic study. The mechanism of the intrinsic (gene) and extrinsic factor (cytokine, microenvironment) affecting the NSC, and some progress on this field in the current years were reviewed.
作者 张舸 田东萍
机构地区 汕头大学医学院病理学教研室
出处 《医学研究生学报》 CAS 2004年第9期847-851,共5页 Journal of Medical Postgraduates
关键词 神经干细胞 分化 诱导 Neural stem cells Differentiation Induction
分类号 R329.26 [医药卫生—人体解剖和组织胚胎学]
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参考文献26

  • 1[1]Gage FH.Mammalian Neural Stem Cells[J]. Science,2000,287(5457):1433-1438.
  • 2[2]Kintner C.Neurogenesis in embryos and in adult neural stem cells[J]. Neurosci,2002,22(3):639-643.
  • 3[3]Briscoe J,Ericson J.Specification of neuronal fates in the ventral neural tube[J]. Curr Opin Neurobiol,2001,11(1):43-49.
  • 4[4]Panchision DM,Pickel JM,Studer L et al .Sequential actions of BMP receptors control neural precursor cell production and fate[J].Genes,2001,15(16):2094-2110.
  • 5[5]Muroyama Y,Fujihara M,Ikeya M et al .Wnt signaling plays an essential role in neuronal specification of the dorsal spinal cord[J].Genes,2002,16(5):548-553.
  • 6[6]Dahmane N,Sanchez P,Gitton Y et al .The Sonic Hedgehog-Gli pathway regulates dorsalbrain growth and tumorigenesis[J].Development,2001,128(24):5201-5212.
  • 7[7]Dietrich J,Easterday MC.Developing concepts in neural stem cells[J].Trends Neurosci,2002,25(3):129-131.
  • 8[8]Nguyen L,Rigo JM,Rocher V et al .Neurotransmitters as early signals for central nervous system development[J].Cell Tissue Res,2001,305(2):187-202.
  • 9[9]Vicario-Abejon C,Collin C,Tsoulfas P et al .Hippocampal stem cells differentiate into excitatory and inhibitory neurons[J].Neurosci,2000,12(2):677-688.
  • 10[10]Caldwell MA,He X,Wilkie N et al . Growth factors regulate the survival and fate of cells derived from human neurospheres[J].Nature Biotechnol,2001,19(5):475-479.

同被引文献9

  • 1[2]Jin K,Minami M,Lan JQ,et al.Neurogenesis in dentate subgranular zone and rostral subventricular zone after focal cerebral ischemia in the rat[J].Proc Natl Acad Sci USA,2001,98(8):4710-4715.
  • 2[3]Zea LE,Weinstein PR,Carlson S,et al.Reversible middle cerebral artery occlusion without craniectomy in rats[J].Stroke,1989,20(1):84-91.
  • 3[4]Berderson JB,Pitts LH,Tsuji M,et al.Rat middle cerebral artery occlusion:evaluation of the model and development of a neurologic examination[J].Stroke,1986,17 (3):472-476.
  • 4[5]Yang HK,Sundholm-Peters NL,Goings GE,et al.Distribution of doublecortin expressing cells near the lateral ventricles in the adult mouse brain[J].J Neurosci Res,2004,76 (3):282-295.
  • 5[6]Ostenfeld T,Svendsen CN.Requirement for neurogenesis to proceed through the division of neuronal progenitors following differentiation of epidermal growth factor and fibroblast growth factor-2-responsive human neural stem cells[J].Stem Cells,2004,22(5):798-811.
  • 6[7]Zachary I.Neuroprotective role of vascular endothelial growth factor:signalling mechanisms,biological function,and therapeutic potential[J].Neurosignals,2005,14(5):207-221.
  • 7[8]Ming GL,Song H.Adult neurogenesis in the mammalian central nervous system:functionality and potential clinical interest[J].Med Sci Monit,2005,11 (7):RA247-252.
  • 8[9]Siegenthaler JA,Miller MW.Transforming growth factor betal modulates cell migration in rat cortex:effects of ethanol[J].Cereb Cortex,2004,14(7):791-802.
  • 9[10]Zhang H,Vutskits L,Calaora V,et al.A role for the polysialic acid-neural cell adhesion molecule in PDGF-induced chemotaxis of oligodendrocyte precursor cells[J].J Cell Sci,2004,117(Pt 1):93-103.

引证文献1

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医学研究生学报
2004年 第9期

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