妇科肿瘤病人维生素E含量的检测

DETECTION OF VITAMIN E LEVELS IN PATIENTS WITH GYNECOLOGICAL TUMORS

①目的 探讨维生素E(VitE)与妇科良、恶性肿瘤间的关系及VitE的潜在抗肿瘤机制。②方法采用紫外线分光光度计检测 12 2例妇科良、恶性肿瘤病人血清VitE的含量。③结果 宫颈癌组与子宫肌瘤组、卵巢癌组与卵巢良性肿瘤组、卵巢癌组与子宫肌瘤组VitE含量有显著差异 (F =5 .94 ,q =3.6 8～ 5 .5 9,P <0 .0 5 ) ;恶性肿瘤病人VitE含量较良性肿瘤病人低 (t=2 .92 ,P <0 .0 5 )。④结论 人体内VitE含量与肿瘤发生有关 。

Objective To investigate the association between vitamin E(Vit E) and gynecological benign or malignant neoplasms, and the potential anti-tumor mechanism of the vitamin. Methods Serum Vit E in 122 patients with gynecological benign or malignant neoplasms was detected by ultraviolet-visible spectrophotometry. Results Vit E levels differed significantly between the cervical cancer and leiomyoma group, between the ovarian cancer and ovarian benign neoplasms group, and between the ovarian cancer and leiomyoma group (F=5.94, q=3.68-5.59, P<0.05). The Vit E level in the patients with malignant tumors was lower than in those with benign tumors (t=2.92, P<0.05). Conclusion Vit E content is associated with oncogenesis, which has a potential anti-tumor effect.