云南地方性暴发性心肌炎疫区人群柯萨奇B组病毒抗体水平调查

Investigation on Ab Against CBV of People in Endemic Fulminating Myocarditis Areas of Yunnan

目的 对 2 0 0 2年发生云南地方性暴发性心肌炎地区的患者、死者及高危人群的急性期和恢复期血清分别进行CBV -IgG ,IgM抗体的测定。 方法 采用间接ELISA法。结果 病区人群和非病区健康人群的CBV -IgM抗体阳性率分别为 3 8.8%( 94/2 42 )和 6.67%( 3 /4 5 ) ,两者之间差异有统计学意义 ( χ2 =17.5 6,P <0 .0 1) ,确诊病例和死者血清的阳性率为 5 9.0 9%( 13 /2 2 ) ,与对照血清之间的差异同样存在统计学意义 ( χ2 =11.78,P <0 .0 1) ;共检测 48份病区高危人群血清的CBV -IgG抗体 ,阳性率为 2 7.0 8%( 13 /4 8)。

Objective Investigation on the CBV-IgG,CVB-IgM of people from Endemic Fulminating Myocarditis (YEFM) areas in Yunnan. MethodThe CBV-IgG,CVB-IgM were detected by ELISA. ResultThe positive rate of CBV-IgM was 38.8% in 242 sera of people from the YEFM areas. The positive rate of CBV-IgM was 59.09% in 22 sera from the patients and deeds. The positive rate of CBV- IgM was 6.67% in 45 sera of people from the non-YEFM area. There was highly significantce in statistics between them(χ 2 =17.56,P<0.01;χ 2=11.78,P<0.01).The positive rate of CBV-IgG was 27.08% in 48 sera of people from the YEFM areas. ConclusionThe Ab level against CBV in the YEFM areas are higher than that in the non-YESMD areas.