期刊文献+

伐地那非治疗勃起功能障碍的有效性和安全性 被引量:10

Efficacy and Safety of Vardenafil for Men with Erectile Dysfunction
下载PDF
导出
摘要 伐地那非是一种有效的、高选择性的口服磷酸二酯酶 (PDE5 )抑制剂。它对各种病因、各种程度、各年龄段的男性勃起功能障碍 (ED)患者均有良好疗效 ,可显著改善勃起功能。该药口服后最快 10min即可起效 ,长期使用仍能保持疗效 ,不良反应少 ,耐受性好。因此 ,伐地那非是治疗男性ED患者的有效、安全的药物。 Vardenafil is an oral, potent, highly selective phosphodiesterase 5 (PDE5) inhibitor. It improves erectile function significantly regardless of the etiology and severity of erectile dysfunction(ED) or the age of the patients. Its onset time leading to successful intercourse is as short as 10 minutes after administered orally, and in most patients it works persistently. Adverse reactions are generally transient and mild to moderate in nature. So vardenafil is both effective and safe for men with ED .
作者 朱积川 姜辉
出处 《中华男科学杂志》 CAS CSCD 2004年第9期704-710,共7页 National Journal of Andrology
关键词 伐地那非 磷酸二酯酶5抑制剂 勃起功能障碍 有效性 安全性 vardenafil PDE5 inhibitor erectile dysfunction efficacy safety
  • 相关文献

参考文献11

  • 1Ayta IA, McKinlay JB, Krane RJ. The likely worldwide increase in erectile dysfunction between 1995 and 2025 and some possible policy consequences[J]. BJU Int, 1999, 84(1): 50-56.
  • 2Nehra A, Kulaksizoglu H. Global perspectives and controversies in the epidemiology of male erectile dysfunction [J]. Cuur Opin Urol, 2002, 12(6): 493-496.
  • 3Hellstrom WJ, Gittelman M, Karlin G, et al. Vardenafil for treatment of men with erectile dysfunction: efficacy and safety in a randomized, double-blind, placebo-controlled trial [J]. J Androl, 2002, 23(6) :763-771.
  • 4Donatucci C, Pommerville P, Niederberger C, et al. Vardenafil improved patient satisfaction with erection hardness, orgasmic function, and sexual experience in men with erectile dysfunction [J]. J Urol, 2003, 169(Supp14): 246.
  • 5Valiquette L, Hellstrom W, Gittelman M. Vardenafil provides reliable efficacy over time in men with erectile dysfunction [J]. Int J Impot Res, 2002, 14(Suppl 3): S88.
  • 6Stief C, Porst H, Saenz de Tejada Ⅰ, et al. Sustained efficacy and tolerability with vardenafil over 2 years of treatment in men with erecitle dysfunction[J]. Int J Clin Pract, 2004, 58 (3): 230- 239.
  • 7Padm a-Nathan H, Eardley Ⅰ, Collins O, et al. Vardenafil restores normal functioning to men with erectile dysfunction [J]. J Urol,2002, 167(4 Suppl): 177.
  • 8Goldstein Ⅰ, Young JM, Fishcher J, et al. Vardenafil, a new phosphodiesterase type 5 inhibitor, in the treatment of erectile dysfunction in men with diabetes: a multicenter double-blind pla cebo-controlled fixed-dose study [J]. Diabetes Care, 2003, 26 (3): 777-783.
  • 9Porst H, Rosen R, Padma-Nathan H, et al. The efficacy and tolerability of vardenafil, a new, oral, selective phosphodiesterase type 5 inhibitor, in patients with erectile dysfunction: the first athome clinical trail[J]. Int J Impot Res, 2001 , 13 (4): 192-199.
  • 10Kloner RA, Mohan P, Norenberg C, et al. Cardiovascular safety of vardenafil, a potent, highly selective PDE-5 inhibitor in patients with erectile dysfunction: an analysis of five placebo-controlled clinical trials [J]. Pharmacotherapy, 2002, 22 (10):1371.

同被引文献92

引证文献10

二级引证文献55

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部