4Van Meerten E, Verweij J, Schellens JH. Antineoplastic agents:Drug interactions of clinical significance.Drug Saf, 1995,12(3):168.
5Ireland A, Priddle JD, Jewell DP. Acetylation of 5-aminosalicylic acid by isolated human colonic epithelial cells.Clin Sci, 1990,78(1):5.
6Williams L, Davis JA, Lowenthal DT. The lnfluence of food on the absorption and metabolism of drugs. The Medical Clinics of North America: Clinical Nutrition,1993,815.
7Ameer B, Weintraub RA. Drug lnteractions with grapefruit Juice. Clin Pharmacokinet,1997,33(2): 103.
1[1]Waxman D J. Rat hepatic cytochrome P-450 isoenzyme 2c[J]. J Biol Chem, 1984,259:15481-15490.
2[2]Waxman D J, Dannan G A, Guengerich F P. Regulation of rat hepatic cytochrome P- 450: Age- dependent Expression,Hormonal Imprinting, and Xenobiotic Inducibility of Sexspecific isoenzymes[J]. Biochemistry, 1985,24:4409-4417.
3[3]Belina H, Cooper S D, Farkas R, et al. Sex difference in the phospholipid composition of rat liver microsomes [J].Biochem Pharmacol, 1975,24: 301-303.
4[4]Turcan R G, Tamburini P P, Gibson G G, et al. Drug metabolism, cytochrome P450 spin state, and phospholipid changes during pregnancy in the rat[J]. Biochem Pharmacol,1981,30: 1223-1225.
5[5]Conney A H. Induction of microsomal enzymes by foreign chemicals and carcinogenesis by polycyclic aromatic hydrocarbons: G. H. A. Clowes Memorial Lecture[J]. Cancer Res,1982,42 : 4875-4917.
6[6]Shapiro B H. Sexually dimorphic response of rat hepatic monooxygenases to low-dose Phenobarbital[J]. Biochem Pharmacol, 1986,35: 1766-1768.
7[7]Dannan G A, Guengerich F P. Immunochemical comparison and quantitation of microsomal Flavin-containing monooxygenases in various hog, mouse, rat, rabbit, dog, and human tissues[J]. Molec Pharmacol, 1982,22 : 787-794.
8[8]Denlinger C L, Vesell E S. Hormonal regulation of the developmental pattern of epoxide hydrolases[J]. Biochem Pharmacol, 1989,38:603-610.
9[9]Kim S G, Cho J C, Jung K H. Differential expression of rat microsomal epoxide hydrolase gene by imidazole and triazole antimycotic agents [J]. Drug Metab Dispos, 1995, 23: 460-464.
10[10]Los L E, Welsh D A, Heroid E G, et al. Gender differences in toxicokinetics, liver metabolism, and plasma esterase activity: observations from a chronic(27-week) toxicity study of enalapril/diltiazem combinations in rats[J].Drug Metab Dispos,1996,24:28-33.