持续正压通气治疗对OSAHS睡眠结构的影响

Effect of CPAP on the sleep structure of obstruction sleep apnea-hypopnea syndrome

目的 :研究阻塞性睡眠呼吸暂停低通气综合征 (OSAHS)患者睡眠结构及持续正压通气治疗(CPAP)对OSAHS睡眠结构的影响 ,探讨患者白天嗜睡等症状的原因。方法 :将 5 8例OSAHS患者 ,经CPAP治疗前后的 32例OSAHS患者及 18例正常对照进行睡眠监测。结果 :OSAHS患者 1期睡眠明显增多 ,3+4期睡眠明显减少 ,REM睡眠减少 ,夜间醒觉时间明显延长 ,睡眠周期不全。经CPAP治疗后醒觉时间及 1期睡眠减少 ,2期睡眠、深度睡眠、REM睡眠增加。结论 :OSAHS有明显的深睡眠及REM睡眠剥夺 ,CPAP治疗能使紊乱的睡眠结构及破碎的睡眠进程得到一定程度的恢复。

Objective: To study the sleep structure of the patients suffering from obstruction sleep apnea-hypopnea syndrome(OSAHS),effect of continue positive airway pressure(CPAP) on the sleep structure of OSAHS patients, to explore the reason that patients feel drowsy in daytime. Method:The sleep of 58 OSAHS,32 OSAHS before and after CPAP,18 normal control were monitored.Results: Patients with OSAHS had sleep structure disturbance obviously. Sleep stage 1and awakening time increased, but stage 3+4 and REM sleep decreased obviously. The sleep cycle wasn′t sufficient. After CPAP treatment, the sleep stage 1 and awakening time decreased, the sleep stage 2, stage 3+4 and REM sleep increased. Conclusion: Patients with OSAHS have obvious deprivation of deep and REM sleep; CPAP make it recover in some degree that disorder sleep structure and broken sleep proceeding.