1[1]Hayashi N, Ito I, Yanagisawa A, et al. Genetic diagnosis of lymph-node metastases in colorectal cancer [J]. Lancet, 1995,345 (8960): 1257-1259.
2[2]Greenson JK, Isenhart CE, Rice R, et al. Identification of occult micrometastases in pericolic lympt nodes of Dukes'B colorectal cancer patients using monoclonal antibodies against cytokeratin and CC49: Correlation with long-term survival[J]. Cancer, 1994,73(3) :563-569.
3[3]Lindemann F, Schlimok G, Dirschedl P, et al. Prognostic significance of micrometastatic tumor cells in bone marrow of colorectal cancer patients[J]. Lancet, 1992,340(8821 ): 685-689.
4[4]Cutait R, Alves VAF, Lopes LC, et al. Restaging of colorectal caner based on the identification of lymph node micrometastases though immunoperoxidase staining of CEA and cytokeratins[J]. Dis Colon Rectum, 1991,34(10) :917-920.
5[5]Cote R J, Houchens DP, Hitchcock CL, et al. Intra operative detection of occult colon cancer micrometastases using 125 I-radiolabeled monoclonal antibody CC49 [J] .Cancer, 1996,77(4):613-620.
6[6]Arnold MW, Yong DC, Hitchcock CL, et al. Radioimmunoguided surgery in primary colorectal carcinoma:a bioprognostic indicator independent of traditional staging[ J]. Am J Surg, 1995,170(4) :315-318.
7[7]O'Sullivan GC,Collins JK,Kelly J, et al. Micro metastases:marker of metastatic potential or evidence of residual disease [J]. Gut, 1997,40(4) :512-515.
8[8]Smith B, Selby P, Southgate J, et al. Detection of melanoma cells in peripheral blood by means of reverse transcriptase and polvmerase chain reaction[J]. Lancet, 1991,338(8777): 1227-1229.
9[9]Gerhard M, Juhl H, kalthoff H, et al. Specific detection of carcinoembryonic antigen-expressing tumor cells in bone marrow aspirates by polymerase chain reaction[J]. J Clin Oncol, 1994,12(4) :725-729.
10[10]Mori M,Mimori K,Inoue H,et al . Detection of cancer micrometastases in lymph nodes by revere transcrip-tsse-polymerase chain reaction[J].Cancer Rees, 1995,55(15) :3417-3420.
