肿瘤患者ESBLs细菌感染抗生素治疗的临床研究

Study of Clinical treatment by antibiotics of ESBLs bacterium infection in tumor patients

目的 :探讨合理使用抗生素对减少肿瘤患者合并产超广谱β-内酰胺酶 (extendedspectrumβ-lacta mases,ESBLs)细菌感染的意义。方法 :比较在得到药敏报告前后 ,临床医生的抗生素使用情况。结果 :大肠埃希菌产ESBLs率为13.3 % ;肺炎克雷伯菌产ESBLs率为15.2 %。根据药敏报告结果调整抗生素的使用。结论 :抗生素的合理使用是减少肿瘤患者合并ESBLs细菌感染的措施之一。

Objective:To investigate whether rational using antibiotic can reduce the infection of ESBLs bacˉterium infection in tumor patients.Methods:The differences of antibiotic using were contrasted before and after obtaining the drug sensitivity reports.Results:The rate of E.coli producing ESBLs is13.3%;while the rate of K.pneumoniai producing ESBLs is 15.2%.The used drugs were regulated according to the report of drug-sensitivity.Conclusion:One of the reasons for the low separation rate of ESBLs producing bacteria in this hosˉpital was the rational using antibiotic.