部分性脾栓塞治疗脾功能亢进

Partial splenic embolization in the treatment of hypersplenism

目的:研究部分性脾栓塞治疗脾功能亢进的临床价值。方法:对47例脾功能亢进患者行周围性部分性脾栓塞,栓塞剂为医用明胶海绵,栓塞前后测定血细胞数量,并做方差分析和t检验。结果:7例儿童栓塞范围为65%～75%,2例青年Child分级A级患者栓塞了75%,6例肝癌伴脾亢者为40%左右,其余均在50%～60%之间。术后24h、72h、1周、2周、4周、3月、6月复查血白细胞和血小板均较栓塞前明显升高(P<0.05),未出现严重并发症。结论:部分性脾栓塞治疗脾功能亢进安全、显效、并发症少。术中多次造影分次追加能防止过度栓塞和栓塞不足。

Objective To evaluate the clinical valuation of partial splenic embolization in the treatment of hypersplenism.Methods All the fourty-seven cases with hypersplenism was given peripheral partly splenic embolism,the embolus was Gelfoam,pre-and post-splenic embolism,we investigate the blood rutine,especially the count of WBC and PLT,and give analysis of variance and t test. Results The area of splenic embolism in 7 children was 65%～75%,in 2 young patients with liver function Child A was 75%,in 6 primary livertumor with hypersplenism was about 40%,and the other's area of splenic embolism was 50%～60%. Post-operative 24hr,72hr,1 week,2 weeks,4 weeks,3 months,6 months,the counts of WBC and Plt elevated obvious compared preoperative(P<0.05),and have no complications. Conclusion Partial splenic embolization in the treatment of hypersplenismis safety,effective,almost no complication,intraoperative,multiple splenic artery angiography could control the area of splenic embolism,preventing the inappropriate embolism.