咪唑安定与氯胺酮在小儿骶麻中的复合应用

A clinical study of ketamine combined medazlom on children's plexus sacralisanesthesia

目的:观察咪唑安定在小儿基础麻醉复合骶管阻滞中的作用。方法:选择2003年9月～2004年8月2～10岁的小儿下腹部手术40例,随机分为M、N组,每组20例,两组入手术室后肌注氯胺酮4～6mg·kg-1后行0.25%布比卡因0.8mg·kg-1单次骶管注射。M组术中间断静注氯胺酮1～2mg·kg-1维持,N组手术开始前,咪唑安定0.1mg·kg-1。术中根据患儿心率及体动情况间断静注氯胺酮1～2mg·kg-1。结果:M、N两组麻醉效果评价N组明显优于M组(P<0.01)。麻醉苏醒时间两组无明显差异(P>0.05)。结论:氯胺酮合用咪唑安定可使麻醉安静平稳。

Objective To investigate the effects of midazolam on children accepted basic anesthesia combine plexas sacralis . Methods Sixty children aged from 2 to 10 years undergoing lower abdominal surgery were randomly divided into two groups in operation room (M and N).Children were injected in ktamine(4～6 mg·kg-1)used 0.25%Bupricaine(0.8 mg·kg-1) in plesus sacralis in operationroom.The children in group M were administered interavenously ketamine needly.The children in guoup N were administered ketamine 1～2 kg and medzolam 0.1mg/kg before operation.The children in froup N were daministed ketamine 1～2 mg/kg needly during operation. Result The anesthesia effect of group N is significantly better than that of group M (P<0.01)Conclusion The combination of midazolam with ketamine is helpful to maintain conthesia stable and quite.