血吸虫病不同流行类型地区人群血吸虫病与HBV感染的关系及其流行规律分析

Analysis of the Relationship between Schistosomiasis and HBV Infection and Their Epidemic Features in Different Schistosome Epidemic Regions

目的探讨血吸虫病不同流行程度地区人群血吸虫病与乙型肝炎的关系及其流行规律。方法采用Dot-ELISA检测血吸虫CAb、CAg及ELISA法检测HBV5项指标。结果血吸虫病流行区、控制区、非流行区受检者HBV阳性率分别为24.0%、37.7%、31.9%。控制区和非流行区显著高于流行区。流行区血吸虫感染人群HBV阳性率(23.4%)与未感染血吸虫人群阳性率(24.3%)无显著差异,但合并感染都集中在Cab形成的人群中。结论各地HBV感染与环境因素及该地区对疾病的认识与预防有关。血吸虫病与乙型肝炎似乎无明显的内在联系,但有外在的协同作用。

Objective To study on the relationship between schistosomiasis and HBV infection and their epidemic features in different schistosome epidemic region. Method Adopt Dot ELISA to examine schistosome CAb, CAg and adopt ELISA method to examine the 5 HBV indexs. Results The HBV positive rates of the individuals from schistosome epidemic area, control area and non epidemic area are 24.0%,37.7%and 31.9%respectively. The ratio for positive result in control area and non epidemic area is much higher than in epidemic area. In epidemic area, the HBV positive rates of the schistosome infected individuals and the non infected individuals are 23.4%and 24.3%respectively, showing no significant different. However, with both HBV and schsitosome infection mainly occurs in the CAb positive population. Conclusions HBV infection is related to the environmental factors and the prevention and peoples understanding of the disease of that region. The schistosomiasis does not have obvious relationship with HBV infection but may change the environmental condition of the region.