摘要
观察了慢性束缚应激法对70%乙醇灌胃致大鼠胃粘膜损伤的影响。结果表明:慢性束缚应激可明显对抗乙醇对大鼠胃粘膜的损伤;双侧膈下迷走神经切除对其保护作用无影响,而腹腔交感神经切除则使其保护作用完全丧失。提示慢性束缚应激对大鼠胃粘膜的保护作用可能是由交感神经介导实现的。
The effect of chronic restraint stress (CRS)on gastric mucosal damage by ethanol in rats wasobserved. The results showed that the gastric mucosal damage by ethanol was significantly attenuatedafter the rats had received CRS for 4 or 7 days. The protection of CRS was not affected in rats withvagotomy but disappeared in sympathectomized rats. It suggests that the gastric mucosal protection ofCRS against ethanol damage is probably mediated through the sympathetic nerve.
出处
《河南医科大学学报》
1993年第3期204-206,共3页
Journal of Henan Medical University
基金
河南省卫生厅科研基金
关键词
应激
细胞保护
胃粘膜
乙醇
stress
cytoprotection
gastric mucosa
ethanol
vegetative nerve
