经颅多普勒(TCD)用于先兆子痫和子痫的预测以及治疗效果的研究

The TCD ultrasound technique for monitoring preeclampsia and eclampsia as well as therapeutic effect

目的:探讨TCD在预测子痫和先兆子痫以及监测治疗效果中的应用价值。方法:选择100例孕妇为研究对象,根据其大脑中动脉血流速度的不同,分为A、B、C 3组,通过每组先兆子痫和子痫的发病率,得出大脑中动脉血流速度和发病率之间的关系。结果:①大脑中动脉血流速度越快,先兆子痫和子痫的发病率越高(X2=17.05 P<0.05);②通过治疗后大脑中动脉血流速度下降(t=10.27 P<0.05)。结论:TCD通过监测大脑中动脉血流速度的变化,能预测子痫和先兆子痫的发生,并能监测治疗效果。

Objective: To evaluate the change maternal middle cerebral artery flow velocities serially by means of TCD ultrasound, monitor cerebrovascular vasospasm and stenosis so as to predict preeclampsia and eclampsia and monitor therapeutic effect. Methods: Choosing 56 patients who were familia of PIH -syndrome and had inclination for catching PIH-syndrome. The other 44 patients who caught PIH, added up to 100 cases. According to maternal middle cerebral artery velocrametry, 100 patients were distributed into three groups: A, B and C. According the standard of practice of transcranial Doppler ultrasound, their MCA mean velocity increased gradually. Through the incidence, drew a conclusion between MCA mean velocity and incidence of preeclampsia, eclampsia. Results: ①The more quickly the MCA mean velocity, the higher the incidence of preeclampsia and eclampsia (X2 = 17. 05, P<0. 05) . ②Comparing the velocities through the TCD technique, can drew a conclusion that MCA mean velocity decreased after treatment (t = 10. 27, P<0. 05) . Conclusion: TCD ultrasound provides evidence of maternal middle cerebral artery flow velocity increased because of cerebrovascular and eclapsia and monitoring therapeutic effect through the change of MCA mean velocity.