糖尿病患者定量超声骨量分布的研究

Quantitative ultrasound bone assessement in diabetic patients

本文对１６７例糖尿病（ＤＭ）患者进行了定量超声骨量（ＱＵＳ）研究。结果表明，ＤＭ患者ＳＯＳ、ＳＤ值均显著低于健康对照组（ｐ＜０．０１），且ＩＤＤＭ患者的ＳＯＳ峰值比ＮＩＤＤＭ患者的ＳＯＳ峰值低（ｐ＜０．０５），表明ＤＭ患者伴有不同程度骨钙、磷代谢异常，最终导致骨质疏松症（ＯＰ）。结果还显示，女性ＤＭ患者低于男性患者ＳＯＳ、ＳＤ（ｐ＜０．０５），表明女性ＤＭ患者更易受多种因素的影响，导致骨矿含量明显降低。因此对ＤＭ患者应同时服用治疗ＯＰ的药物。

We performed quantitive ultrasound in 167 cases of diabetes mellitus (DM). The results indicated that the speed of sound (SOS) and SD in NIDDM group were significantly lower than those in normal group(p<0.01). The peak of SOS in IDDM group was lower than in NIDDM group(p<0.05). We concluded from the results that calcium (Ca)and phosphorus (P) metabolism in DM group was abnormal, which gave rise to osteoporosis, especially in female DM group. We consider that DM patients should be treated with the drugs for DM in combination with those for osteoporosis.