两面针中生物碱的分离

Alkaloids from Zanthoxylum nitidum

目的 :研究两面针的化学成分。方法 :采用硅胶柱层析及重结晶的方法分离和纯化化合物 ,根据理化性质和波谱方法鉴定结构。结果 :从两面针的酸水提取氯仿萃取部分分离得到 8个化合物 ,其中 7个生物碱 ,分别为oxyavicine(1) ,氧化两面针碱 (oxynitidine ,2 ) ,二氢白屈菜红碱 (dihydrochelerythrine ,3) ,去 N 甲基白屈菜红碱 (N norchelerythrine ,4 )和茵芋碱 (skimmianine ,5 ) ,haplopine(6 ) ,liriodenine(7) ,1个木脂素L 芝麻素 (L sesamin ,8)。结论 :化合物 1、3和

AIM:To study the constituents of Zanthoxylum nitidum. METHOD: The compounds were isolated by chromatography and recrystal methods and their structures were elucidated by spectral methods RESULT: Eight compounds were obtained,seven of which were alkaloids.They were identified as oxyavicine(1),oxynitidine(2),dihydrochelerythrine(3), N norchelerythrine(4),skimmianine(5),haplopine(6),liriodenine(7)and L sesamin(8) CONCLUSION:Compounds 1,3 and 6 were obtained from Zanthoxylum nitidum for the first time