轻度低温治疗27例弥漫性轴索损伤病人的临床疗效

Clinical effect of mild hypothermia for 27 patients with diffuse axonal injury

目的 探讨早期使用轻度低温治疗中、重型弥漫性轴索损伤(DAI)病人的疗效。方法 对我科收治的27例中、重型弥漫性轴索损伤病人,早期使用冰毯机降温至轻度低温(35℃～35.5℃)脑保护,加用冬眠Ⅰ号等药物配合治疗,但不使用呼吸机和肌松剂。结果 17例存活,10例死亡。存活病人中恢复良好11例,重残6例。结论 该方法适合于基层医院或条件相对不足的医疗单位,仍能取得良好疗效。

Objective To discuss the clinical effect of mild hypothermia on the patients with moderate or severe diffuse axonal injury (DAI) in the acute stage. Methods 27 patients with moderate or severe DAI caused by head trauma, whose rectus temperature were maintained at 35℃～35.5℃, were treated with cooling blanket and hibernation drugs but without breathing apparatus and muscle relaxants. Results 11 patients had a good recovery and 6, severe disability; 10 patients died. Conclusion Mild hypothermia with hibernation drugs is an effective means for patients with moderate or severe diffuse axonal injury, especially in the local hospitals with poor medical conditions.