腹腔镜胆囊切除术对机体红细胞免疫功能和T淋巴细胞亚群的影响

Effect of laparoscopic cholecystectomy on immune system of erythrocyte and T-lymphocyte subpopulation

目的 :探讨腹腔镜胆囊切除术 (LC)对机体红细胞免疫功能和T淋巴细胞亚群的影响。方法 :以红细胞C3 b受体花环率、红细胞免疫复合物花环率、肿瘤红细胞花环率及CD3、CD4、CD8细胞作为观测指标 ,测定 6 0例LC患者术前、术后第 1天和第 3天免疫指标的变化。结果 :LC患者术后第 1天的上述免疫指标虽有轻度障碍 ,但没有显著性意义 ,且术后第 3天迅速恢复。结论 :LC患者手术前后红细胞免疫功能和T淋巴细胞免疫功能没有明显障碍 。

Objective:To study the effect of laparoscopic cholecystectomy(LC)on human immune system of erythrocyte and T-lymphocyte subpopulation.Methods:The immunologic functions of erythrocyte and T-lymphocyte sub-population in60patients with LC were tested,taking the rate of RBC-C 3 b receptor rosette(RCRR),RBC-immune complex rosette(RICR),tumor-RBC rosette(TRR)and CD3,CD4,CD8cells as observation indexs.Results:In1d after operation,the immunologic functions of erythrocyte and T-lymphocyte subpopulation in patients with LC were degraded slightly.But there was no statistical difference,and the indexs recovered immediately on3d after operation.Conclusions:The effect of LC on human immune system of erythrocyte and T-lymphocyte subpopulation is no obvious.This study supply immediate recovery of patients after LC with immunologic evidence.