心绞痛患者冠状动脉造影与血管内超声的对比分析

Comparison of coronary angiography with intravascular ultrasound imaging

目的 :应用选择性冠状动脉造影和血管内超声 (IVUS)对心绞痛患者的冠状动脉病变进行临床对比分析。方法 :对 1 2 5名有典型心绞痛的患者进行选择性冠状动脉造影和血管内超声检测 ,按心绞痛性质分为稳定型心绞痛组 (SA组 )和不稳定型心绞痛组 (UA组 ) ,比较两组患者冠状动脉狭窄程度、斑块形态和性质的差异。结果 :冠状动脉造影显示的病变血管及狭窄程度两组比较差异无统计意义 ,但是血管内超声显示 ,UA组病变以脂质斑块多见 ,SA组病变则以纤维斑块和钙化斑块多见 ,UA组病变自发性内膜撕裂和血栓形成的比例明显高于SA组。结论 :IVUS对于不稳定型心绞痛患者的冠状动脉粥样硬化斑块病变特点的诊断明显优于冠状动脉造影 。

Objective To compare coronary angiography(CAG) and intravascular ultrasound (IVUS). Methods One hundred and twenty five patients with typical angina who underwent CAG and IVUS were divided into stable angina group (Group SA) and unstable angina group (Group UA). Angiographic feature and ultrasound imaging were compared the two groups.Results Coronary angiography showed no significant differences in the diseased artery and the degree of stenosis between the 2 groups. Intravascular ultrasound revealed that there were significantly more soft lesions in group UA than in Group SA, and that fibrous and calcific lesions were more prevalent in Group SA. Spontaneous dissection and thrombus were more frequently found in Group UA than in group SA.Conclusion IVUS is superior to CAG for studying characteristics of coronary atherosclerotic plaque. IVUS is more important than CAG in selecting indications of coronary artery interventional operation.