不同年龄急性心肌梗死患者血脂水平分析

Study of Serum Lipid Level in the Different Age Patients with Acute Myocardial Infarction

目的探讨不同年龄急性心肌梗死(AMI) 患者血脂水平状况。方法将208 例AMI 患者分为青年组(31～44 岁,26例)、中年组(年龄45～59岁,51例)、老年组(60～79岁,112例)、高龄老年组(80～89岁,19 例) ;检测各年龄组总胆固醇( TC) 、甘油三脂( TG) apoAI、apoB水平,血脂增高检出率,分析血脂与AMI发病年龄之间的关系。结果TC、TG水平随AMI 发病年龄增加而降低, TG、TC与AMI发病年龄之间呈负相关,相关系数分别为r=-0.1872和r=-0.1501(P<0.001和P<0.0l), apoAI、apoB与发病年龄之间无明显相关性,P均>0.05。中、青年组及老年组TC均值极显著高于高龄老年组( P <0.01),中、青年组TG均值显著高于其他两组( P <0.05),TC水平在青年组与高龄老年组之间差异有显著性意义(P<0.O1),在其余各组之间差异无显著性意义。结论重视CHD ,特别是中青年组病人的调脂治疗,调脂治疗为CHD 二级预防的重要措施。

Objective To detect the relationship of serum lipid levels and age in patients with acute myocardial infarction (AMI). Methods Two hundreds and eight patients with AMI were divided into young aged group(aged 31～44 , 26 cases) , middle aged group(aged 44～59 , 51 cases) , aged group ( aged 60～79 , 1112cases) , and senile group ( aged 80～89 19cases) . Total cholesterol level ( TC) , triglyceride level ( TG) , apoAI and apoB were detected at the same lab . Results TC and TG levels decreased with increasing age. Single factor correlation analysis indicated that TG and TC levels had negative correlation with age(P<0.001,P<0.01),but apoAl and apoB levels had no cor-relativity with age (P>0. 05). Conclusion It is a very important measure to modify lipid for coronary secondary prevention ,especially in young and middle aged patients.