125例肿瘤病人药物不良反应分析

Analysis of Drug Adverse Reaction in 125tumors Patient

目的探讨肿瘤病人发生药物不良反应(ADR)的情况。方法按患者的年龄、性别、用药情况及ADR的主要表现、发生时间、严重程度等进行统计分析。结果125例报表中,男81例,女44例,平均年龄(52.12±5.38)岁,涉及药物68种,主要为抗感染药物(47.2%), ADR主要表现是全身性损害,其次是皮肤及其粘膜的损害,严重损害者8例;用药途径主要是静脉点滴。结论应加强对肿瘤病人ADR的监测工作,以保证用药安全性。

Objective To investigate drug adverse reaction occurred in tumour patient.Ethods Statistical analysis was carried out according to the ages, sex of the cases,drug usage,main manifestation, time of occurrence and level of severity of ADR. Results Of 125cases,81 were male, 44 were female, their average was (52.12±5.38)years old.68drugs were involved.Main drugs were antiinfective drugs (47.2%), next was the drugs forc ardiovascular.Main manifesta-tion of ADR was systemic damage, then was the damage to skin and mucous membrane.8 cases suffered from severe damage .The main way of medication was IV injection. Conclusion Monitoring of ADR in tumr.s patients should be strengthened in order to ensure the safety of drug usage.