氯诺昔康用于甲状腺次全切除病人超前镇痛的临床观察

Clinical observation about preemptive analgesia with lornoxicam for patients undergoing subtotal thyroidectomy

目的研究以氯诺昔康行超前镇痛对甲状腺次全切除手术患者术后疼痛的影响。方法选取择期行甲状腺次全切除的患者40例,随机分成Ⅰ、Ⅱ组,Ⅰ组患者手术前30min予以静脉注射氯诺昔康16mg,术毕静注生理盐水2ml;Ⅱ组则在术前30min静注生理盐水2ml,术毕静脉注射氯诺昔康16mg。以视觉模拟评分法(VAS)对患者术后的疼痛程度进行评分及观察药物的不良反应。结果Ⅰ组术后VAS疼痛评分显著性低于Ⅱ组(P<0.05),两组不良反应发生率的差异无显著性(P>0.05)。结论以氯诺昔康行超前镇痛可用于甲状腺次全切除手术患者,效果确切、不良反应少。

Objective To investigate the effects of preemptive analgesia with lornoxicam on the postoperative pain for patients undergoing subtotal thyroidectomy.Methods 40 cases scheduled for selective surgery of subtotal thyroidectomy were randomly divided into two groups: group Ⅰ received Lornoxicam 16mg 30minutes before operation and N.S 2ml at the end of operation; group Ⅱreceived N.S 2ml 30 minutes before operation and Lornoxicam 16mg at the end of operation. Postoperative pain was assessed by VAS-score at 4? 8? 12? 24 hours after operation,side-effects were assessed.Results The VAS-score of group I is significantly lower than that of group Ⅱ(P < 0.05),the side-effects such as nausea and vomit of two groups have no significant difference(P > 0.05). Conclusion Preemptive analgesia with lornoxicam 16mg provides satisfactory postoperative painful relief with no obvious side-effects for patients undergoing subtotal thyroidectomy.