卵巢无性细胞瘤19例临床与病理分析

Clinical and pathological analyses in 19 cases of ovarian dysgerminoma

目的 研究卵巢无性细胞瘤的临床与病理特征以及预后情况。方法 回顾性分析 1 9例卵巢无性细胞瘤临床与病理资料 ,并随访其预后。结果 术后存活 1 3例 (随访 9～ 30年 ,均为临床Ⅰ期 ) ,术后 1年内死亡 4例 (临床Ⅱ期 2例 ,其中 1例合并卵黄囊瘤 ,另 1例合并梅格斯综合征 ,另临床Ⅲ期、Ⅳ期各 1例 ) ,失访 2例。结论 早期单纯型无性细胞瘤预后好 。

Objective To understand the clinical and pathological characteristics,and prognosis of ovarian dysgerminoma were well acquired for further improvement in medical management.Methods The clinical and pathological data of 19 cases of ovarian dysgerminoma were analyzed retrospectively.All the 19 cases were followed up postoperation.Results After the operation,13 cases were alive(following up to 9～30 years.All cases are in surgical stage Ⅰ).Four cases died within one year after operation(2 cases were in stage Ⅱ,one of them was comlicated with yolk sac tumour,the other was complicated with Meigs' syndrome.Two cases were stage Ⅲ and stage Ⅳ,respectively).There were 2 cases (in clinical stage Ⅱ)which were failed in following up.Conclusions The prognosis is good in simple dysgerminoma with low grade clinical stage,while the prognosis is worge in mixed type dysgerminoma accompanied with high grade clinical stage.