早期梅毒实验室诊断的对比研究

Comparing Studies on the Laboratory Diagnosis of Early Syphilis

目的探讨早期梅毒可靠及时的诊断方法。方法以梅毒螺旋体暗视野检查(D-F)、梅毒螺旋体被动乳胶凝集试验(TPPA)、快速血浆反应素环卡片试验(RPR)3种检查方法对128例一期梅毒及190例二期梅毒分别进行检测并进行对比研究。结果在128例一期梅毒中,D-F阳性107例(83.59%),RPR阳性91例(71.09%),TPPA阳性93例(72.66%)。在190例二期梅毒中,RPR、TPPA均为阳性(100.00%)。结论在一期梅毒诊断中D-F检查,优于RPR及TPPA方法。在二期梅毒诊断中,RPR与TPPA阳性率达(100.00%)。

OBJECTIVE To investigate on the laboratory diagnosis of early syphilis.METHODS examined 128 of primary syphilis and 190 of secondary syphilis by dark field microscopy Treponema Pallidum examination RPR and TPPA which have been extensively applied in clinic now,and compared the results.RESULTS Among 128 cases of primary syphilis,107(83.59%)were dark field assay positive,90(70.31%)were RPR positive,93(72.66%)were TPPA positive.among 190 of secondary syphilis,the positive rate of RPR and TPPA are both 100%.CONCLUSIONS dark field microscopy Treponema Pallidum examination is more sensitive than RPR and TPPA in primary syphilis,the positive rate of RPR and TPPA are both 100%in secondary syphilis.