摘要
探索血清PGⅠ、PGⅡ及GAS的联合检测对胃癌诊断的意义。采用RIA方法测定了 190名正常人和 12 9例胃病患者的血清PGⅠ、PGⅡ和GAS水平 ,其中 6 8例为胃癌患者。结果表明 ,胃癌患者血清PGⅠ水平和PGⅠ /PGⅡ比值明显低于对照组 ,但GAS水平却明显升高。PGⅠ、PGⅡ和GAS联合检测 ,对胃癌诊断的灵敏度可达 94 .2 % ,特异性达到 73.4 %。提示血清PGⅠ、PGⅡ和GAS的检测可作为胃癌的初步筛查手段 ,提高了胃癌的检出率。
To evaluate the clinical value of combined determination of PGⅠ, PGⅡ and GAS for early diagnosis in gastric cancer,the serum levels of PGⅠ, PGⅡ and GAS in 190 healthy controls and 129 gastric patients were measured by RIA. Of 129 patients, 68 caser were gastric cancer.The results showed that the serum levels of PGⅠ and PGⅠ/PGⅡ ratio in gastric cancer patients were obviously lower than that in healthy controls and the serum GAS levels were significantly higher. The sensitivity of combined determination of PGⅠ, PGⅡ and GAS for gastric cancer diagnosis was 94.2% and the specificity 73.4% respectively.All these results indicated that determination of serum PGⅠ,PGⅡ and GAS levels may be used as a tools for primary screening gastric cancer.
出处
《标记免疫分析与临床》
CAS
2004年第3期131-133,共3页
Labeled Immunoassays and Clinical Medicine
