新生儿窒息血清心肌酶的变化

The change of myocardium zyme of newborwn asphyxia

目的 :探讨新生儿窒息患儿血清心肌酶与心肌损害的关系。方法 :将 4 1例新生儿窒息患儿分为轻度窒息组与重度窒息组 ,并选择同期住院无窒息史的 16例患儿作为对照组。采用全自动生化分析仪测定所有患儿及16例无窒息史患儿的血清心肌酶及其同工酶活性。结果 :天冬氨酸转氨酶 (AST)、乳酸脱氢酶 (LDH)、肌酸激酶(CK)、肌酸激酶心肌同工酶 (CK MB)在重度窒息组与轻度窒息组和对照组之间相比差异有统计学意义 (P <0 .0 1) ,且随窒息程度的加重 ,心肌酶及同工酶的水平有逐渐增高的趋势。 结论 :心肌酶水平可作为判断新生儿窒息严重程度和指导治疗的指标。

Objective: To explore the relation between myocardium zyme of newborwn asphyxia and myocardium damage. Methods: 41 cases of pediatrics patients were devided into two groups, including the low asphyxia and the other group of high asphyxia. 15 cases of the control group without asphyxia were hospitalized patients in the same period. All patients were tested myocardiumzyme by OLYMPUS AU400. Result: There were significant differences among three groups (P<0.01). There was a positive coeffient between all zymes include AST, LDH, CK AND CK-MB and the degree of asphyxia. Conclusion: The level of myocardium zyme is a very good mark in judging myocardium damage of newborwn asphyxia.