外部作用力引起组织压动态变化时的毛细血管血流

Capillary Blood Flow with Dynamical Change of Tissue Pressure Caused by Exterior Force

建立了组织压随中医推拿摆动类手法作用力发生动态变化时的毛细血管 -组织血液动力学模型 ,以此来解释中医推拿摆动类手法的血液动力学机制。血液在毛细血管内作低雷诺数流动 ,血浆渗出毛细血管壁遵循Starling定律 ,组织压随实测的滚法推拿作用力线性变化。同时考虑了血液表观黏度、血浆蛋白浓度、红细胞压积。数值计算了组织压动态变化时的毛细血管流量、血液表观黏度、渗透率和渗透因子 ,并和静态组织压的相应变量进行比较。结果显示 ,组织压动态变化导致毛细血管血流量有所增大 ,而血液表观黏度将下降 ,定性说明了中医摆动类手法的“活血化瘀”血液动力学机制。

A hemodynamic model of capillary and tissue, in which tissue pressure changed with swing manipulation of Traditional Chinese Medical Massage(TCMM), is presented in this paper to explain the hemodynamic mechanism of swing manipulation. Blood flowed in capillary with low Reynolds number. Plasma exuded through capillary according to the Starling's Law. Tissue pressure changed linearly with the massage force measured. Blood apparent viscosity, plasma protein concentration and red cell's hematocrit were taken into account. Capillary flow rate, blood apparent viscosity, filtration rate and filtration fraction with dynamical change of tissue pressure were calculated numerically, and were compared with those in static tissue pressure condition. Results showed that, dynamical change of tissue pressure led to the increase of capillary flow rate and the decrease of blood apparent viscosity, which qualitatively explained the hemodynamic mechanism of “promoting blood circulation and removing blood stasis” in swing manipulation of TCMM.