支气管药物激发试验对不典型哮喘的诊断价值

Diagnostic Value of Bronchial Provocation Tests in Asthmatic Patients with Atypical Symptoms

目的 观察支气管激发试验对临床不典型哮喘的诊断价值。方法 对临床肺功能、支气管扩张试验不能确诊的病人 ,用乙酰甲胆碱行支气管激发试验 ,明确诊断。结果 4 0例临床以咳嗽、胸闷为主要表现的病人 ,肺功能FEV1.0 /FVC %≥ 70 % ,但激发试验 11例阳性 (2 7.5 % ) ,2 9例阴性 (72 .5 % )。结论 (1)乙酰甲胆碱支气管激发试验是诊断不典型哮喘的有效手段 ;(2 )对临床高度怀疑哮喘的不典型哮喘而基础肺功能正常的病人 。

Objective To observe the diagnostic value of bronchial provocation tests for asthmatic patients with atypical symptoms.Methods The mechacholine provocation tests were applied to patients whom couldnt be diagnosed by lung function test and bronchiectasis test.Results The bronchial provocation test showed positive in 11 cases out of the 40 patients(27.5%)with chough and suffocating symptoms and FEV1.0/FVC%≥70% of lung test while negative in 29 cases(72.5%).Conclusions The methacholine provocation test is effective in diagnosing the asthmatic patients with atypical symptoms;the bronchial provocation test should be the first choice in diagnosing the patients highly suspicious of asthma with atypical symptoms and having good base lung function.