HPV的致瘤机制与泛蛋白蛋白酶体系统
Human papillomavirus-induced carcinogenesis and the ubiquitin-proteasome system
摘要
人类乳头瘤病毒 (HPV)与宫颈癌及其他人类恶性肿瘤的发生有关。这些致瘤性HPV的致瘤潜力依赖于早期基因E6和E7的产物 ,它们通过泛蛋白 蛋白酶体系统分别降解肿瘤抑制基因蛋白 p5 3、pRb和其他PDZ结构域蛋白 ,从而达到致瘤的目的。
出处
《国外医学（肿瘤学分册）》
2004年第11期821-824,共4页
Foreign Medical Sciences (Cancer Section)
基金
教育部留学回国人员科研启动基金 ( 682 3 0 0 10 0 4)
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