高血压病患者B型超声主动脉壁厚度与血清载脂蛋白的相关性

The Corrclation between Aorta Wall Thickness in B-Mode Ultra-Sonography and Serumal Apolipoproteins in Patients with Primary Hypertension

采用 Mark-600型超声诊断仪测量了128例高血压病患者主动脉壁厚度(AWT),并同时检测了血脂指标,结果显示,高脂血症组血清 apoB 及 AWT 均显著高或厚于血脂正常组(P<0.01),其 apoAI/apoB 比值显著低于血脂正常组(P<0.01),临床合并冠心病的患病率亦显著高于血脂正常组(P<0.05)。相关性分析显示,AWT 与 apoB(r=0.338)呈直线正相关,与 apoAl(r=-0.385)及apoAl/apoB(r=-0.540),呈直线负相关,(P 均<0.01)。经逐步回归分析,筛选对 AWT 有显著作用的血脂指标,结果依次为 apoAl/apoB、apoB。

The aorta wall thickness(AWT) was measured with Mark-600 mode ultasonography in 128 pa- tients with primary hypertension.The blood lipid level was simutaneously determined.The results showed that compared with normal lipidemina group,serumal apo B and AWT were increased(all P< 0.01),the ratio of apoAI/apoB was decreased (P<0.01),and the prevalence rate of oronary heart disease was elevated(P<0.05),in hyperlipidemia group.The correlation analysis suggested that AWT has a linear positive correlation with apoB(r=0.338),and a linear negative correlation with apoAI(r =-0.385) and apoA I/apoB(r=-0.540)(all P<0.01).A stepwise regression analysis showed that blood lipid parameters which play a significant role in AWT were sifted out.The results are suc- cessively apoAI/apoB,apoB.