摘要目的探究不宁腿综合征(Restless Legs Syndrome RLs)的临床特点,治疗及预后。方法对已确诊的18例RLS进行回顾性分析。结果RLS在临床上并不少见,其中不明原因者占72.22%,有原发病者占27.78%,如贫血、妊娠、下肢静脉曲张、糖尿病。病因治疗及多巴胺类药物治疗有效。痊愈者占66.67%,好转者占33.33%。结论RLS预后好。
1[1]Hening WA. Restless legs syndrome: diagnosis and treatment[J]. Hos p Med, 1997,54-75.
2[2]Rothdach AJ, Trenkwalder C, Haberstock J,et al. Prevalence and risk factors of RLS in an elderly population: memory and morbidity in augsburg elderly[J]. N eurology, 2000,54:1064-1068.
3[3]Winkelman JW, Chertow GM, Lazarus JM. Restless legs syndrome in end stage renal disease[J]. Am J Kidney Dis, 1996,28:372-378.
4[4]Goodman JD, Brodie C, Ayida GA. Restless leg syndrome in pregnancy[ J]. BMJ, 1988,297:1101-1102.
5[5]Hening W, Allen R, Earley C,et al. The treatment of restless legs sy ndrome and periodic limb movement disorder[J]. Sleep, 199 9,22:970-999.
6[6]Hornyak M, Voderholzer U, Hohagen F,et al. Magnesium therapy for per iodic leg movements-related insomnia and restless legs syndrome: an open pilot study[J]. Sleep, 1998,2 1:501-505.
7[7]Hargrave R, Beckley DJ. Restless leg syndrome exacerbated by sertral ine[J]. Psychosomatics, 1998,39:177-178.
8[8]Aul EA, Davis BJ, Rodnitzky RL. The importance of formal serum iron studies in the assessment of restless legs syndrome[J]. Neurology, 1998,51:912.
9[9]Earley CJ, Connor JR, Beard JL,et al. Abnormalities in CSF concentra tions of ferritin and transferring in restless legs syndrome[J]. Neurology, 2000,54:1698-1700.
10[10]National Heart, Lung and Blood Institute Working Group. Restless legs Syndrome detection and management in primary care[J]. Am Fam Phys, 2000,6 2:108-114.