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抗增殖药物涂层支架预防和治疗支架内再狭窄的临床研究进展 被引量：1

Advances in Clinical Trials about Stents Coated with Antiproliferative Agents for the Prevention and Treatment of In-Stent Restenosis
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摘要 支架内再狭窄是介入治疗中的难题。新近多个有关雷帕霉素、紫杉醇涂层支架的临床试验显示药物涂层支架能有效预防支架内再狭窄。其对复杂病变的疗效有待于进一步研究。
作者 曲志刚 廖德宁
机构地区 第二军医大学长征医院心内科
出处 《心血管病学进展》 CAS 2004年第5期393-396,共4页 Advances in Cardiovascular Diseases
关键词 支架内再狭窄 药物涂层支架 预防和治疗 临床研究进展 抗增殖 雷帕霉素 临床试验 紫杉醇
分类号 R541.4 [医药卫生—心血管疾病]
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参考文献21

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同被引文献17

  • 1司同国,贺能树.药物涂层支架防治血管再狭窄的临床研究进展[J].放射学实践,2004,19(7):537-539. 被引量：1
  • 2Marx SO, Marks AR. The development of rapamycin and its application to stent restenosis[J ] . Circulation,2001,104(11) :852.
  • 3Sousa JE,Costa MA,Abizaid A,et al .Lack of neointimal proliferation after implantation of sirolimus - coated stents in human coronary arteries[J]. Circulation,2001,103(2) :192.
  • 4Rensing BJ, Vos J,Smite PC, et al . Coronary restenosis elimination with a sirolimus eluting stent - first European human experience with 6-month angiographic and intravascular ultrasonic follow- up[J]. Eur Heart J ,2001,22(2) :2 125.
  • 5Sousa JE,Costa MA,Abizaid AC,et al .Sustained suppression of neointimal proliferation by sirolimus- eluting stents: one- year angiographic and intravascular ultrasound follow - up[J ] . Circulation, 2001,104(17):2 007.
  • 6Degertekin M,Serruys PW,Foley DP,et al .Persistent inhibition of neointimal hyperplasia after sirolimus- eluting stent implantation: long- term(up to 2 years)clinical, angiographic, and intravascular ultrasound follow - up[J ]. Circulation, 2002,106(13) :1 610.
  • 7Grube E,Bullesfeld L. Initial experience with paclitaxel- coated stents[J ] .J Interv Cardiol,2002,15(6) :471.
  • 8Axel DI, Kunert W, Goggelmann C, et al .Paclitaxel inhibits arterial smooth muscle cell proliferation and migration in vitro and in rive using local drug delivery[J ]. Circulation, 1997,96(2) :636.
  • 9Drachman DE,Edelman ER,Seifert P, et al .Neointimal thickening after stent delivery of paclitaxel: change in composition and arrest of growth over six months[J ].J Am Coll Cardiol,2000,36(7):2 325.
  • 10Heldman AW, Cheng L, Jenkins GM, et al .Paclitaxel stent coating inhibits neointimal hyperplasia at 4 weeks in a porcine model of coronary restenosis[J ]. Circulation, 2001,103(18): 2 289.

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心血管病学进展
2004年 第5期

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