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瘢痕疙瘩手术加放射治疗复发因素分析 被引量:4

Factors related to recurrence of keloid after postoperative radiotherapy
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摘要 目的分析瘢痕疙瘩术后放射治疗的疗效。方法回顾分析术后放射治疗的83例瘢痕疙瘩患者的复发情况。采用SAS6.12软件,以瘢痕疙瘩术后放射治疗后的复发与否为应变量,性别、年龄、病变部位、病变面积、开始照射时间、放射治疗方法为自变量,对其进行Logistic逐步回归分析。结果瘢痕疙瘩术后放射治疗复发与病变面积和开始照射时间相关,而与性别、年龄、病变部位等无关。结论采用几种疗效肯定的放射治疗方法治疗术后的瘢痕疙瘩,其复发与病变大小和开始照射时间相关。 Objective To report on the outcome of postoperative radiotherapy of keloid. Methods The recurrence rate of 83 patients with keloid which had been treated by surgery and postoperative radiotherapy were retrospectively reviewed with χ 2 check and stepsise LOGISTIC regression using software SAS 6.12. Results Recurrence of keloid after postoperative radiotherapy was correlate with size of lesion and interval after operation but not with sek,age or site of lesion. Conclusions With any an authentic method of postoperative radiotherapy,recurrence of keloid would only be correlated with size of lesion and interval after operation.
出处 《中华放射肿瘤学杂志》 CSCD 北大核心 2004年第3期219-221,共3页 Chinese Journal of Radiation Oncology
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  • 1Dustan HP. Does keloid pathogenesis hold the key to understanding black/white differences in hypertension severity? Hypertension, 1995,26(6 Pt 1 ):858-862.
  • 2Murray JC. Scars and keloids. Dermatol Clin, 1993, 11 (4) :697-708.
  • 3Ghazizadeh M, Miyata N, Sasaki Y, et al. Silver-stained nucleolar organizer regions in hypertrophic and keloid scars. Am J Dermatopathol,1997, 19(5) :468-472.
  • 4Alaish SM, Yager DR, Diegelmann RF, et al. Hyaluronic acid metabolism in keloid fibroblasts. J Pediatr Surg, 1995, 30(7) :949-952.
  • 5Marneros AG, Norris JE, Olsen BR, et al. Clinical genetics of familial keloids. Arch Dermatol, 2001, 137 ( 11 ): 1429-1434.
  • 6Saed GM, Ladin D, Olson J, et al. Analysis of p53 gene mutations in keloids using polymerase chain reaction-based single-strand conformational polymorphism and DNA sequencing. Arch Dennatol, 1998, 134(8) :963-967.
  • 7Nirodi CS, Devalaraja R, Nanney LB, et al. Chemokine and chemokine receptor expression in keloid and normal fibroblasts. Wound Repair Regen, 2000, 8(5) :371-382.
  • 8Peltonen J, Hsiao LL, Jaakkola S, et al. Activation of collagen gene expression in keloids: co-localization of type Ⅰ and Ⅵ collagen and transforming growth factor-beta 1 mRNA. J Invest Dermatol, 1991,97(2) :240-248.
  • 9Igarashi A, Nashiro K, Kikuchi K, et al. Connective tissue growth factor gene expression in tissue sections from localized scleroderma,keloid, and other fibrotic skin disorders. J Invest Dermatol, 1996,106(4) :729-733.
  • 10Xue H, McCauley RL, Zhang W. Elevated interleukin-6 expression in keloid fibroblasts. J Surg Res, 2000, 89( 1 ) :74-77.

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