摘要
采用香猪肝细胞免疫山羊，制备成抗肝细胞抗血清。实验香猪分成３组：第１组从脉系膜静脉内注入抗血清，按２．５ｍｌ／ｋｇ给药；第２组注入相同量的正常山羊血清；第３组通过胃管给四氯化碳，按５００ｍｇ／ｋｇ给药，取肝脏做光镜及透射电镜检查，第１组表现为典型的急性肝炎，第２组肝脏结构正常，第３组表现为小叶中央型坏死。
ini swines and goats were used in experiments. The goats
were immunized with hepatoevesfrom mini swines to prepare antisera. The mini swines were
divided into three groups.Animan ofgroup 1 were injected with antisera at a dose of
2.5ml/kg,animal of group 2 were injected withnormal goat sera at a dose of 2.5/kg,and an
intragastric instillation of carbon tetrachloride wasperformed on mini swines of group 3 at a
dose of 500 mg/kg. The specimens of their livers werestudied by light and transmission
electron microscopes.The animals of group 1 have typical features of acute hepatitis of human
being,group 2 have a normal liver structure,and group 3 havelesions located at the centre of
lobule.
出处
《南京铁道医学院学报》
CAS
1994年第1期8-11,共4页
Journal of Nanjing Railway Medical College
