P物质抑制剂在增生性疤痕中的应用

Substance P restraining drug injecting therapeutics to treat the hyperplasic scar

了解P物质抑制剂在治疗增生性疤痕中的疗效。 [方法 ] 从 1998年到 2 0 0 0年 6月应用传统注射激素疗法治疗增生性疤痕患者 178例 ,同期运用注射P物质抑制剂治疗增生性疤痕患者 137例 ,进行疗效比较。[结果 ] 接受P物质抑制剂治疗的患者 ,疤痕评分平均下降 34 % ,运用传统激素治疗方法的患者治疗前后平均评分下降 2 3% ,且运用P物质抑制剂治疗的复发率为 18 7% ,传统的激素注射疗法治疗复发率为 76 5 %。 [结论 ] 在治疗增生性疤痕时应首选P物质抑制剂。

Objective] To compare the curative effect of the traditional injecting bormonal drug and substance P restraining drug injecting therapeutics to treat the hyperplastic scar.[Method] using traditional injecting therapeutics to treat 178 cases of sufferers and substance P restraining drug to treat 137 cases of sufferers with injecting therapeutics from 1998 to June 2000.[Result] following one year, we found the grade of the sufferers of accepting substance P restraining drug decreased 34%.The grade of the sufferers who accepting traditional hormonal treatment decreased 23%. Using substance P restraining drug injecting the recrudescent rate was 18.7%. Using traditional injecting therapeutics the recrudescent rate was 76.5%.[Conclusion] we shall choose substance p restraining drug when we are treating the hyperplastic scar with the injecting therapeutics