复方甘草酸苷对胆道结石术后退黄的临床效果观察

The Effect of Compound Glycyrrhizin on Jaundice after Cholelithes Operation

目的 :评价复方甘草酸苷对胆道结石并发阻塞性黄疸患者手术后的退黄效果。方法 :观察和检测41例胆总管结石并发阻塞性黄疸患者 (观察组 )术后第1d～15d ,在应用复方甘草酸苷后胆汁引流量和肝功能变化情况 ;对照组未应用复方甘草酸苷。结果 :观察组术后的胆汁引流量较对照组提前3d达到稳定 ,且胆汁颜色也较对照组深 ;术后第7d开始 ,观察组所有肝功能指标较对照组均明显降低 (P<0 05)。结论 :复方甘草酸苷有助于胆道结石并发阻塞性黄疸患者术后黄疸的提前减退和肝功能的尽早恢复。

OBJECTIVE:To observe the effect of compound glycyrrhizin on patients with cholelithes combined with obˉstructive jaundice.METHODS:The changes of bile drainage and liver function in41patients with choledocholith and obstrucˉtive jaundice were observed on1to15days after operation(the trial group).The control group did not receive compound glyˉcyrrhizin.RESULTS:The bile drainage of the trial group arrived to stable state3days earlier than that of the control group and color of bile was darker than that of control group;The liver function of trial group was significantly better than that of the control group from the7th day after operation(P<0.05).CONCLUSION:The application of compound glycyrrhizin can proˉmote the declining of jaundice and improve the recovery of liver function in patients with cholelithes combined with obstructive jaundice after operation.