ICU内嗜麦芽窄食单胞菌肺部感染的危险因素与预防

Study on the risk factors and prevention of pulmonary infection of stenotrophomonas maltophilia in ICU

目的探讨ICU内嗜麦芽窄食单胞菌肺部感染的危险因素和预防。方法对 18例ICU内嗜麦芽窄食单胞菌肺部感染的发病情况、高危因素以及预防措施等进行统计分析。结果 18例多发生于基础疾病入ICU后的 2～4周内 ,药敏提示对多种常用抗生素耐药 ,临床治疗预后欠佳 ,关键在于有效预防。结论嗜麦芽窄食单胞菌肺部感染ICU内危重病人为易感人群 ,常伴有较严重的基础疾病 ,加强监护病房的消毒 ,切断外源性传播途径 ;严格无菌操作 ,减少内源性感染 ;降低高危因素及合理应用广谱抗生素 ,尤在感染出现后应选择敏感性高的药物或联合用药 ,对提高危重症抢救的成功率具有重要意义。

Objective To explore the risk factor and prevention of pulmonary infection stenotrophomonas maltophilia in ICU. Method Statistic analysis have been used for studying pathogenesis, risk factors and preventive measure in 18 patients suffering from pulmonary infection of stenotrophomonas maltophillia in ICU. Result Clinical manifestation mostly appeared during 2-4weeks after entering ICU. According to antibiotic sensibility test, it made no response to many common antibiotics. Efficient prevention became the key point due to the bad clinical prognosis after clinical treatment. Conclusion Patients in ICU are easily affected group with severe disease. Therefore, It is important to strengthen sterilization and asepsis operation in ICU to cut off both outer and inner transition, and to reduce risk factors and use broad antibiotics reasonably, especially when infection appears, more sensible antibiotics and combined medication should be the first choice for improving saving quality in ICU.